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before propensity score matching
|
after propensity score matching
|
|---|
|
≥ 2 drugs (n = 9,711)
|
1 drug (n = 29,938)
|
p
|
Standard mean difference
|
≥ 2 drugs (n = 6,044)
|
1 drug (n = 6,044)
|
p
|
Standard mean difference
|
|---|
|
Sex
| | |
< 0.0001*
|
0.0985
| | |
0.5788
|
0.0100
|
|
Male
|
5683 (0.5861)
|
16037 (0.5373)
| | |
3561 (0.5892)
|
3591 (0.5941)
| | |
|
Female
|
4014 (0.4139)
|
13809 (0.4627)
| | |
2483 (0.4108)
|
2453 (0.4059)
| | |
|
Age (year)
| | |
< 0.0001*
| | | |
0.9991
| |
|
< 10
|
669 (0.0693)
|
1671 (0.0563)
| | |
358 (0.0592)
|
363 (0.0601)
| | |
|
10
|
462 (0.0479)
|
1183 (0.0399)
| | |
285 (0.0472)
|
265 (0.0438)
| | |
|
20
|
477 (0.0494)
|
1586 (0.0534)
| | |
238 (0.0394)
|
225 (0.0372)
| | |
|
30
|
599 (0.0621)
|
2367 (0.0797)
| | |
344 (0.0569)
|
341 (0.0564)
| | |
|
40
|
723 (0.0749)
|
2186 (0.0736)
| | |
455 (0.0753)
|
448 (0.0741)
| | |
|
50
|
1256 (0.1302)
|
3506 (0.1181)
| | |
812 (0.1343)
|
819 (0.1355)
| | |
|
60
|
2095 (0.2171)
|
5787 (0.1949)
| | |
1382 (0.2287)
|
1399 (0.2315)
| | |
|
70
|
2195 (0.2275)
|
6903 (0.2325)
| | |
1476 (0.2442)
|
1485 (0.2457)
| | |
|
80
|
1047 (0.1085)
|
3821 (0.1287)
| | |
636 (0.1052)
|
643 (0.1064)
| | |
|
90
|
122 (0.0126)
|
669 (0.0225)
| | |
57 (0.0094)
|
55 (0.0091)
| | |
|
100
|
3 (0.0003)
|
7 (0.0002)
| | |
1 (0.0002)
|
1 (0.0002)
| | |
|
Height (cm)
| | |
< 0.0001*
| | | |
0.9998
| |
|
< 10
|
0 (0.0000)
|
0 (0.0000)
| | |
0 (0.0000)
|
0 (0.0000)
| | |
|
10
|
0 (0.0000)
|
1 (0.0001)
| | |
0 (0.0000)
|
0 (0.0000)
| | |
|
20
|
3 (0.0005)
|
1 (0.0001)
| | |
2 (0.0003)
|
1 (0.0002)
| | |
|
30
|
31 (0.0050)
|
19 (0.0010)
| | |
15 (0.0025)
|
15 (0.0025)
| | |
|
40
|
22 (0.0035)
|
44 (0.0024)
| | |
20 (0.0033)
|
21 (0.0035)
| | |
|
50
|
21 (0.0034)
|
44 (0.0024)
| | |
20 (0.0033)
|
26 (0.0043)
| | |
|
60
|
29 (0.0047)
|
62 (0.0033)
| | |
28 (0.0046)
|
27 (0.0045)
| | |
|
70
|
52 (0.0084)
|
111 (0.0060)
| | |
48 (0.0079)
|
47 (0.0078)
| | |
|
80
|
46 (0.0074)
|
85 (0.0046)
| | |
43 (0.0071)
|
45 (0.0074)
| | |
|
90
|
53 (0.0085)
|
88 (0.0047)
| | |
49 (0.0081)
|
51 (0.0084)
| | |
|
100
|
42 (0.0068)
|
98 (0.0053)
| | |
40 (0.0066)
|
41 (0.0068)
| | |
|
110
|
42 (0.0068)
|
114 (0.0061)
| | |
42 (0.0069)
|
39 (0.0065)
| | |
|
120
|
58 (0.0093)
|
132 (0.0071)
| | |
58 (0.0096)
|
62 (0.0103)
| | |
|
130
|
102 (0.0164)
|
403 (0.0217)
| | |
99 (0.0164)
|
88 (0.0146)
| | |
|
140
|
747 (0.1202)
|
2449 (0.1319)
| | |
727 (0.1203)
|
723 (0.1196)
| | |
|
150
|
1889 (0.3038)
|
5975 (0.3218)
| | |
1847 (0.3056)
|
1824 (0.3018)
| | |
|
160
|
2108 (0.3391)
|
6222 (0.3351)
| | |
2058 (0.3405)
|
2084 (0.3448)
| | |
|
170
|
890 (0.1432)
|
2477 (0.1334)
| | |
868 (0.1436)
|
871 (0.1441)
| | |
|
180
|
81 (0.0130)
|
238 (0.0128)
| | |
79 (0.0131)
|
79 (0.0131)
| | |
|
190
|
1 (0.0002)
|
4 (0.0002)
| | |
1 (0.0002)
|
0 (0.0000)
| | |
|
≥ 200
|
0 (0.0000)
|
0 (0.0000)
| | |
0 (0.0000)
|
0 (0.0000)
| | |
|
Weight (kg)
| | |
0.0003*
| | | |
0.9916
| |
|
< 10
|
200 (0.0264)
|
369 (0.0177)
| | |
117 (0.0194)
|
120 (0.0199)
| | |
|
10
|
264 (0.0348)
|
620 (0.0298)
| | |
162 (0.0268)
|
165 (0.0273)
| | |
|
20
|
190 (0.0250)
|
470 (0.0226)
| | |
119 (0.0197)
|
113 (0.0187)
| | |
|
30
|
597 (0.0787)
|
1683 (0.0808)
| | |
437 (0.0723)
|
438 (0.0725)
| | |
|
40
|
1813 (0.2390)
|
4929 (0.2366)
| | |
1498 (0.2478)
|
1492 (0.2469)
| | |
|
50
|
2213 (0.2917)
|
6176 (0.2964)
| | |
1844 (0.3051)
|
1851 (0.3063)
| | |
|
60
|
1506 (0.1985)
|
4135 (0.1985)
| | |
1204 (0.1992)
|
1212 (0.2005)
| | |
|
70
|
559 (0.0737)
|
1672 (0.0802)
| | |
457 (0.0756)
|
465 (0.0769)
| | |
|
80
|
156 (0.0206)
|
503 (0.0241)
| | |
132 (0.0218)
|
131 (0.0217)
| | |
|
90
|
47 (0.0062)
|
157 (0.0075)
| | |
44 (0.0073)
|
32 (0.0053)
| | |
|
100
|
15 (0.0020)
|
62 (0.0030)
| | |
9 (0.0015)
|
10 (0.0017)
| | |
|
110
|
12 (0.0016)
|
19 (0.0009)
| | |
10 (0.0017)
|
6 (0.0010)
| | |
|
120
|
4 (0.0005)
|
7 (0.0003)
| | |
1 (0.0002)
|
0 (0.0000)
| | |
|
130
|
0 (0.0000)
|
3 (0.0001)
| | |
0 (0.0000)
|
0 (0.0000)
| | |
|
140
|
4 (0.0005)
|
3 (0.0001)
| | |
3 (0.0005)
|
2 (0.0003)
| | |
|
150
|
3 (0.0004)
|
11 (0.0005)
| | |
3 (0.0005)
|
3 (0.0005)
| | |
|
160
|
3 (0.0004)
|
7 (0.0003)
| | |
3 (0.0005)
|
4 (0.0007)
| | |
|
170
|
0 (0.0000)
|
5 (0.0002)
| | |
0 (0.0000)
|
0 (0.0000)
| | |
|
180
|
0 (0.0000)
|
2 (0.0001)
| | |
0 (0.0000)
|
0 (0.0000)
| | |
|
190
|
0 (0.0000)
|
0 (0.0000)
| | |
0 (0.0000)
|
0 (0.0000)
| | |
|
≥ 200
|
1 (0.0001)
|
2 (0.0001)
| | |
1 (0.0002)
|
0 (0.0000)
| | |
|
Sepsis
| | |
< 0.0001*
|
0.2190
| | |
0.7867
|
0.0048
|
|
1
|
799 (0.0823)
|
953 (0.0318)
| | |
478 (0.0791)
|
470 (0.0778)
| | |
|
0
|
8912 (0.9177)
|
28985 (0.9682)
| | |
5566 (0.9209)
|
5574 (0.9222)
| | |
