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Table 3 Results of geospatial additive regression by selected congenital anomalies combined spatial error and spatial lag (SARAR) models

From: Broad Spectrum epidemiological contribution of cannabis and other substances to the teratological profile of northern New South Wales: geospatial and causal inference analysis

Parameter Model
Parameter Estimate (C.I.) P-Value Parameters Value P-Value
Atrial Septal Defect
 Cannabis 0.04 (0.01, 0.07) 0.0078 phi 0.0706 NA
   psi 4.4E-05 0.9999
   rho 0.0373 0.9400
   lambda −0.8526 0.0291
CHROMOSOMAL Defects
 Cannabis 0.04 (0.01, 0.07) 0.0227 phi 0.0072 0.9998
 Tobacco −0.03 (−0.06, 0) 0.0404 psi 2.1E-05 0.9999
   rho 0.2018 0.7175
   lambda −0.2621 0.6308
Diaphragmatic_Hernia
 Cannabis 0.06 (0.01, 0.11) 0.0269 phi 0.0135 0.9994
   psi 1.4E-05 1.0000
   rho 0.6731 0.0333
   lambda −0.7513 0.0436
Downs Syndrome
 Cannabis 0.09 (0.05, 0.14) 2.7E-05 phi 0.0135 NA
 Binge_Alcohol −2.02 (−3.34, −0.7) 0.0027 psi −2.0E-05 0.9999
   rho −0.7249 0.1285
   lambda 0.0633 0.8845
Gastroschisis
 Cannabis 0.07 (0.02, 0.11) 0.0029 phi 0.0116 0.9996
   psi −2.6E-05 0.9999
   rho −0.2004 0.7327
   lambda −0.0568 0.9039
Hypospadias
 Cannabis −0.09 (− 0.16, − 0.03) 0.0034 phi 0.2884 NA
   psi −0.0001 0.9996
   rho 0.0213 0.9665
   lambda −0.6716 0.0760
Patent Ductus Arteriosus
 Cannabis 0.03 (0, 0.06) 0.0365 phi 0.1043 0.9957
   psi 2.1E-05 0.9999
   rho −0.5223 0.4700
   lambda −0.76625 0.1705
Tetralogy Fallot
 Cannabis 0.08 (0.04, 0.13) 0.0005 phi 0.1269 NA
   psi −0.0001 0.9998
   rho 0.5305 0.1006
   lambda −0.3621 0.4032
Ventricular Septal Defect
 Tobacco −0.03 (− 0.05, 0) 0.0166 phi 0.0068 0.9995
   psi 4.4E-06 1.0000
   rho −0.9832 0.0135
   lambda −0.3843 0.3813
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BMC Pharmacology and Toxicology

ISSN: 2050-6511

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