The effect of multidrug exposure on neurological manifestations in carbamazepine intoxication: a nested case-control study

Table 1 Sociodemographic and clinical characteristics of patients with carbamazepine intoxication. Continuous variables are presented as average ± SEM, ordinal variables are presented as number and percentage

	All patients	Neurological Symptoms
	(n = 80)	Non-Severe (n = 70)	Severe (n = 10)	p-value*
Age (Years)	43.4 ± 2.0	45.2 ± 2.1	30.0 ± 3.5	0.00
Gender (% female)	38 (47.5)	32 (45.7)	4 (40)	0.39
Ethnicity:				0.03
Arab	25 (31.3)	24 (34.3)	1 (10)
Jews	54 (67.5)	46 (66.7)	8 (80)
Others	1 (1.3)	0	1 (10)
Smokers	6 (7.5)	6 (8.9)	0 (0)	0.196
Chronic Carbamazepine users	67 (83.8)	59 (84.3)	8 (80)	0.32
Indications for carbamazepine:
Epileptic seizures	50 (62.5)	47 (67.1)	4 (40)	0.09
Psychiatric disorder	27 (33.7)	20 (28.5)	7 (70)	0.013
Neuropathic pain	4 (5)	4 (5.7)	0 (0)	0.29
Others^a	5 (6.2)	5 (7.1)	0 (0)

*P-value was calculated by t-tests for continuous variables and Chi-square test for ordinal variables
^aOthers- primary sclerosis, psychomotor retardation and accidental ingestion

ISSN: 2050-6511