Novel coumarins active against Trypanosoma cruzi and toxicity assessment using the animal model Caenorhabditis elegans

Table 1 Importance of each GRIND descriptor of the Model

Autoscaled coefficient	Descriptor	Field	Distance range
−0.427	193	DRY-O	3.6–4.0
−0.363	261	DRY-N1	12.4–12.8
0.325	151	TIP-TIP	5.2–5.6
−0.319	170	TIP-TIP	12.8–13.2
0.313	20	DRY-DRY	8.0–8.4
0.307	163	TIP-TIP	10.0–10.4
0.305	455	N1-TIP	16.4–16.8
0.271	456	N1-TIP	16.8–17.2
0.224	8	DRY-DRY	3.2–3.6
−0.195	169	TIP-TIP	12.4–12.8
0.148	285	DRY-TIP	3.6–4.0

ISSN: 2050-6511